Pharmacology

1.       Principles of Pharmacology: Altered biochemistry and structure in disease and how drugs can help, How they move in body – Pharmacokinetics, Optimal – Dose, frequency, duration of treatment, drug interactions, Classification – which drugs in which class, Their CNS CVS RESP GIT HEPATIC RENAL BLOOD METABOLISM Effects, Probability of their occurrence, which are therapeutic, side effects, or toxicities. Creating Evidence to determine cost, effectiveness, risks, logistics and using it in choice of treatment. Medicolegal and Informed Consent. Reporting Adverse Drug Reactions – Pharmacovigilance.

2.       Main Groups of Drugs:

2.1 CNS – Anesthetics, Antipsychotics, Antiepileptics, For raised or lowered intracranial tension, Neurotropic nutrition supplement's, Anti anxiety, migraine and head ache

2.2 CVS - Antihypertensive, Antiarythmic, Antianginal and MI, LVF, CHF,  Anticoagulant and Fibrinolytics, Shock

2.3 Respiration - Hypersensitivity - Type I, II, III, IV, Anaphylaxis and Bronchial Asthama, Bronchial Pneumonia , Broncheactisis, Emphysema, COPD. Pulmonary embolism, Fat embolism, Pulmonary Hypertension, Covid Pathogenesis.

2.4 GIT - Oral - Mouth washes, Tooth pastes, Mouth ulcers, Gastric Reflux disease, Acid Peptic Disease, Diarrhoea, Constipation, Colic, IBD, IBS, gastrokinetic agents, digestants, carmanatives

2.5 Hepatic -Hepato protective, Portal Hypertension, GB stone

2.6 Renal: Stone, infection, Uremia, Diuretics, Bladder- Hypertonic, Hypotonic, hematuria, infection, Prostate - Benign and Malignant

2.7 Pancreas BILE acid Sequestrants, pacreatic enzyme compositions

2.8 Intestine: Anti worm agents, Anti motility, Pro motality, Inflammatory bowel disease, Anti amebic

2.9 Rectum, Vagina and Uterus- Family planning, Uterine relaxants and stimulants

3.0 Blood: Anemia, Leukemias, Platelet defficiency, coagulopathy, anti coagulants

3.1 Metabolism : Diabetes, Micronutients

3.2 Skeletal: Calcium Metabolism, Osteoporosis, Rickets and Osteomalcia, Arthritis-Infective, TB, Immunological, Gout Degenerative -Cartilage Regenerating Drugs , Nerve- Neuralgia, neurotropics, muscles - cramps, sarcopenia, myaesthenia gravis

3.3Endocrine: Thyroid, pituitary, adrenal, ovary, testes

3.4 Anti Cancer 

3.5 Immunity

3.6 Miconutrients

3.7 Antimicrobials Bacterial, Fungal, Tubercular, Viral, helmenthics, malarials ameba

3.8 Skin and Mucous Membranes

3.9 Recent Advances - Gene therapy, targeted drug delivery, personalised medicine, chrono pharmacology, pharmaco vigilance, pharmacoepidemiology